Speakers
Programme
9:00 - 9:30 Opening Words
KEYNOTE SPEECH
09:30 - 10:30 Jean-Laurent Casanova - "Toward a genetic theory of childhood infectious diseases”
SESSION 1: Nucleic Acid Sensors - Chair: Gunther Hartmann
10:30 - 11:00 Lee Gehrke - "RNAs containing modified nucleotides fail to trigger RIG-I conformational changes for innate immune signaling"
11:00 - 11:30 Coffee break
11:30 - 12:00 Leonie Unterholzner - "cGAS and IFI16: Sensing intracellular DNA as 'stranger' and 'danger' signal"
12:00 - 12:30 Jean-Luc Imler - "Sensing viral RNAs in the model organism drosophila
12:30 - 14:00 Lunch
SESSION 2: RNA Modification - Chair: Maria Ohman
14:00 - 14:30 Michael Jantsch - "Understanding the effects of editing-deficiency"
14:30 - 15:00 Mark Helm - "RNA modifications affect recognition and immunestimulation by TLR7"
15:00 - 15:30 Liam Keegan - "Evolutionarily conserved immune effects of ADAR RNA editing, Conflict RNA Modifications and the RNA-DNA genome transition"
15:30 - 16:00 Coffee break
16:00 - 16:30 Gideon Rechavi - "mRNA modifications beyond RNA editing"
16:30 - 17:00 Mashael Alqasem - "Queuine Insertase tagging and selection in MDA-MB-231 cells via CRISPR and SmartFlare™"
17:00 - 17:30
Nina Papavasiliou - "RNA editing as a mechanism of diversification of cellular populations"
17:30 - 19:00 Poster Session I
SESSION 3: Infectious Diseases - Chair: Michael Jantsch
09:00 - 09:30 Mariano Garcia-Blanco - "The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis"
09:30 - 10:00 Ann-Kristin Östlund Farrants - "Transcriptome and DNA methylome analysis of two sympatric 1 ethic groups with 2 differential susceptibility to Plasmodium falciparum infection living in Burkina Faso"
10:00 - 10:30 Yifat Ofir-Birin - "Cell-cell communication between Plasmodium and host immune DNA sensing pathway via exosomes"
10:30 - 11:00 Mayra Diosa-Toro - "Dengue virus-induced ATF4 expression is independent of eiF2α phosphorylation and SG formation"
11: 00 - 11:30 Coffee break
SESSION 4: Nucleic Acids Modification - Chair: Michael Jantsch
11:30 - 12:00 Reuben Harris - "Cancer Mutagenesis by APOBEC3B and Hypomorphic APOBEC3H"
12:00 - 12:30 Marek Bartošovič - "N6-methyladenosine demethylase FTO targets pre-mRNAs and plays a novel role in nuclear mRNA processing and expression"
12:30 - 14:00 Group Photo and Lunch
SESSION 5: Inflammation - Chair: Drew Weissman
14:00 - 14:30 Roth Shalom Hillel - "A Computational Screen For RNA Editing Alterations In Autoimmune Diseases"
14:30 - 15:00 Osamu Takeuchi - "Posttranscriptional control of inflammatory responses by Regnase-1 and Roquin"
15:00 - 15:30 Jan Rehwinkel - "SAMHD1 limits activation of the cGAS-STING pathway"
15:30 - 16:00 Coffee break
SESSION 6: Disease vectors - Chair: Drew Weissman
16:00 - 16:30 Erika Girardi - "Cross-species comparative analysis of Dicer proteins during Sindbis virus infection"
16:30 - 17:00 Sara Cherry - "RNA viruses are targeted by diverse RNA binding proteins"
17:00 - 17:30 Susan Schuster- "Using CRISPR/Cas9 to unravel the role of mammalian RNAi in antiviral immunity"
17:30 - 18:30 Poster Session II
19:00 Departure to the Mendel Museum and Abbey
20:00 - 22:00 Gala Dinner
KEYNOTE SPEECH
08:30 - 09:30 Caetano Reis e Sousa - "Sensing and restriction of RNA viruses"
SESSION 7: - Towards Therapies Chair: Mark Helm
09:30 - 10:00 Gunther Hartmann - "Identification of the minimal ligand motif for the cytoplasmic DNA sensor cGAS"
10:00 - 10:30 Gregory Heikel - "Exploring the role of the RNA-binding activity of the E3 ubiquitin ligase Trim25 in antiviral innate immunity"
10:30 - 11:00 Coffee break
11:00 - 11:30 Dmitriy Chudakov - "Unique molecular barcoding in BCR and TCR repertoire profiling"
11:30 - 12:00 Drew Weissman - "Nucleoside-modified mRNA-lipid nanoparticle therapeutic protein delivery platform"
12:00 - 12:30 Poster Award
12:30 - 13:30 Lunch
Venue
BEST WESTERN PREMIER Hotel Interantional Brno****
Husova 16, 659 21 Brno, Czech Republic
Website: http://www.hotelinternational.cz/
BEST WESTERN PREMIER Hotel International Brno is a luxury four-star hotel situated beneath Špilberk Castle. It is less than 100 metres from náměstí Svobody (Freedom Square), and is tastefully situated to one side of the historic centre. This important functionalist building from 1962 has been entered onto the list of cultural monuments, and was influenced by pre-war Bauhaus architecture and partly by the Brazilian architect Oscar Niemeyer.
How to get to the International Hotel from the Brno airport
From bus station Letiště Tuřany (Airport Tuřany) by bus nr. 76 to tram station Hlavní nádraží (Main Railway Station), the change for tram nr. 4 to tram station Česká.
How to get to the International Hotel from the Main Bus Terminal Zvonařka
From Zvonařka Main Bus Terminal by tram nr. 12 to tram station Česka.
Useful maps: From the Main Railway station to the International Hotel
From Česká to the International Hotel
From the Hotel Grand - Student Agency bus station to the International Hotel
Sponsors
Abstracts and Posters
Book of Abstracts is HERE to download.